Management of COVID-19 Related Paediatric Blood Samples in a Clinical Haematology Laboratory.
Identifieur interne : 000498 ( 2020/Analysis ); précédent : 000497; suivant : 000499Management of COVID-19 Related Paediatric Blood Samples in a Clinical Haematology Laboratory.
Auteurs : Joyce Ching Mei Lam [Singapour] ; Grace Benjamin Moshi [Singapour] ; Soh Hong Ang [Singapour] ; Hui Ming Chew [Singapour] ; Qing Hui Ng [Singapour] ; Andrew Madjukie [Singapour] ; Logeswary M [Singapour]Source :
- British journal of haematology [ 1365-2141 ] ; 2020.
Abstract
There is currently limited knowledge about the transmission risks of the SARS-CoV-2 virus and its associated disease COVID-19 from routine clinical specimens. The first study to be published on the initial 41 cases of COVID-19 infections admitted in Wuhan detected SARS-CoV-2 RNA in the blood of 6/41 (15%) of patients (Huang et. al., 2020) . However, another study conducted on 1070 clinical specimens collected from confirmed COVID-19 patients in China showed the highest positive rates of SARS-CoV-2 from rRT-PCR testing of respiratory specimens such as bronchoalveolar lavage, sputum and nasopharyngeal swabs (32% - 93%). In contrast, only 1% of blood specimens and none of the urine specimens tested positive (Wang et. al., 2020).
DOI: 10.1111/bjh.16721
PubMed: 32297317
Affiliations:
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Timah Road, Singapore, 229899, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899</wicri:regionArea><wicri:noRegion>229899</wicri:noRegion></affiliation></author><author><name sortKey="Moshi, Grace Benjamin" sort="Moshi, Grace Benjamin" uniqKey="Moshi G" first="Grace Benjamin" last="Moshi">Grace Benjamin Moshi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899</wicri:regionArea><wicri:noRegion>229899</wicri:noRegion></affiliation></author><author><name sortKey="Ang, Soh Hong" sort="Ang, Soh Hong" uniqKey="Ang S" first="Soh Hong" last="Ang">Soh Hong Ang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899</wicri:regionArea><wicri:noRegion>229899</wicri:noRegion></affiliation></author><author><name sortKey="Chew, Hui Ming" sort="Chew, Hui Ming" uniqKey="Chew H" first="Hui Ming" last="Chew">Hui Ming Chew</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, KK Women's and Children's 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Road, Singapore, 229899, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899</wicri:regionArea><wicri:noRegion>229899</wicri:noRegion></affiliation></author><author><name sortKey="M, Logeswary" sort="M, Logeswary" uniqKey="M L" first="Logeswary" last="M">Logeswary M</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899</wicri:regionArea><wicri:noRegion>229899</wicri:noRegion></affiliation></author></analytic><series><title level="j">British journal of haematology</title><idno type="eISSN">1365-2141</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">There is currently limited knowledge about the transmission risks of the SARS-CoV-2 virus and its associated disease COVID-19 from routine clinical specimens. The first study to be published on the initial 41 cases of COVID-19 infections admitted in Wuhan detected SARS-CoV-2 RNA in the blood of 6/41 (15%) of patients (Huang et. al., 2020) . However, another study conducted on 1070 clinical specimens collected from confirmed COVID-19 patients in China showed the highest positive rates of SARS-CoV-2 from rRT-PCR testing of respiratory specimens such as bronchoalveolar lavage, sputum and nasopharyngeal swabs (32% - 93%). In contrast, only 1% of blood specimens and none of the urine specimens tested positive (Wang et. al., 2020).</div></front></TEI><affiliations><list><country><li>Singapour</li></country></list><tree><country name="Singapour"><noRegion><name sortKey="Lam, Joyce Ching Mei" sort="Lam, Joyce Ching Mei" uniqKey="Lam J" first="Joyce Ching Mei" last="Lam">Joyce Ching Mei Lam</name></noRegion><name sortKey="Ang, Soh Hong" sort="Ang, Soh Hong" uniqKey="Ang S" first="Soh Hong" last="Ang">Soh Hong Ang</name><name sortKey="Chew, Hui Ming" sort="Chew, Hui Ming" uniqKey="Chew H" first="Hui Ming" last="Chew">Hui Ming Chew</name><name sortKey="M, Logeswary" sort="M, Logeswary" uniqKey="M L" first="Logeswary" last="M">Logeswary M</name><name sortKey="Madjukie, Andrew" sort="Madjukie, Andrew" uniqKey="Madjukie A" first="Andrew" last="Madjukie">Andrew Madjukie</name><name sortKey="Moshi, Grace Benjamin" sort="Moshi, Grace Benjamin" uniqKey="Moshi G" first="Grace Benjamin" last="Moshi">Grace Benjamin Moshi</name><name sortKey="Ng, Qing Hui" sort="Ng, Qing Hui" uniqKey="Ng Q" first="Qing Hui" last="Ng">Qing Hui Ng</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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